RT Journal Article
SR Electronic
T1 TransRate: reference free quality assessment of de-novo transcriptome assemblies
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 021626
DO 10.1101/021626
A1 Richard Smith-Unna
A1 Chris Boursnell
A1 Rob Patro
A1 Julian M Hibberd
A1 Steven Kelly
YR 2015
UL http://biorxiv.org/content/early/2015/06/27/021626.abstract
AB TransRate is a tool for reference-free quality assessment of de novo transcriptome assemblies. Using only sequenced reads as the input, TransRate measures the quality of individual contigs and whole assemblies, enabling assembly optimization and comparison. TransRate can accurately evaluate assemblies of conserved and novel RNA molecules of any kind in any species. We show that it is more accurate than comparable methods and demonstrate its use on a variety of data.