PT - JOURNAL ARTICLE AU - Richard Smith-Unna AU - Chris Boursnell AU - Rob Patro AU - Julian M Hibberd AU - Steven Kelly TI - <em>TransRate</em>: reference free quality assessment of <em>de-novo</em> transcriptome assemblies AID - 10.1101/021626 DP - 2015 Jan 01 TA - bioRxiv PG - 021626 4099 - http://biorxiv.org/content/early/2015/06/27/021626.short 4100 - http://biorxiv.org/content/early/2015/06/27/021626.full AB - TransRate is a tool for reference-free quality assessment of de novo transcriptome assemblies. Using only sequenced reads as the input, TransRate measures the quality of individual contigs and whole assemblies, enabling assembly optimization and comparison. TransRate can accurately evaluate assemblies of conserved and novel RNA molecules of any kind in any species. We show that it is more accurate than comparable methods and demonstrate its use on a variety of data.