PT - JOURNAL ARTICLE AU - J.A. Llanos-Pérez AU - A. Betancourt-Mar AU - M. P. De Miguel AU - E. Izquierdo-Kulich AU - M. Royuela-García AU - E. Tejera AU - J.M. Nieto-Villar TI - Phase transitions in tumor growth: II prostate cancer cell lines AID - 10.1101/011189 DP - 2015 Jan 01 TA - bioRxiv PG - 011189 4099 - http://biorxiv.org/content/early/2015/02/07/011189.short 4100 - http://biorxiv.org/content/early/2015/02/07/011189.full AB - We propose a mechanism for prostate cancer cell lines growth, e.g., LNCaP and PC3 based on a Gompertz dynamics. This growth exhibits a multifractal behavior and a “second order” phase transition. Finally, it was found that the cellular line PC3 exhibits a higher value the entropy production rate compared to LNCaP, which is indicative of the robustness of PC3, over to LNCaP and may be a quantitative index of metastatic potential tumors.HighlightsCancer is an open, complex, dynamic and self-organizing system.Prostate cancer cell lines growth follows a Gompertz dynamicsProstate cancer cell lines exhibit a multifractal behaviorThe entropy production rate may be considered as metastatic potential marker