PT - JOURNAL ARTICLE AU - Beate Vieth AU - Christoph Ziegenhain AU - Swati Parekh AU - Wolfgang Enard AU - Ines Hellmann TI - powsimR: Power analysis for bulk and single cell RNA-seq experiments AID - 10.1101/117150 DP - 2017 Jan 01 TA - bioRxiv PG - 117150 4099 - http://biorxiv.org/content/early/2017/04/13/117150.short 4100 - http://biorxiv.org/content/early/2017/04/13/117150.full AB - Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in RNA-seq data. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses.