PT - JOURNAL ARTICLE AU - Robert C. Edgar TI - SEARCH_16S: A new algorithm for identifying 16S ribosomal RNA genes in contigs and chromosomes AID - 10.1101/124131 DP - 2017 Jan 01 TA - bioRxiv PG - 124131 4099 - http://biorxiv.org/content/early/2017/04/04/124131.short 4100 - http://biorxiv.org/content/early/2017/04/04/124131.full AB - SEARCH_16S is a new algorithm that annotates 16S ribosomal RNA genes in microbial genomes and metagenomic sequences. Word counting is used to identify candidate segments, then conserved motifs are used to identify homologous loci close to the gene boundaries. SEARCH_16S has >99% sensitivity to known 16S genes.