PT  - JOURNAL ARTICLE
AU  - O le Polain de Waroux
AU  - S Cohuet
AU  - D Ndazima
AU  - A J Kucharski
AU  - A Juan-Giner
AU  - S Flasche
AU  - E Tumwesigye
AU  - R. Arinaitwe
AU  - J Mwanga-Amumpaire
AU  - Y Boum II
AU  - F Nackers
AU  - F Checchi
AU  - R F Grais
AU  - W J Edmunds
TI  - Characteristics of human encounters and social mixing patterns relevant to infectious diseases spread by close contact: A survey in southwest Uganda
AID  - 10.1101/121665
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 121665
4099  - http://biorxiv.org/content/early/2017/03/28/121665.short
4100  - http://biorxiv.org/content/early/2017/03/28/121665.full
AB  - Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet data from low-resource settings remain scarce. We undertook a social contact survey in rural Uganda, whereby participants were asked to recall details about the frequency, type, and socio-demographic characteristics of any conversational encounter that lasted for ≥5 minutes (henceforth defined as ‘contacts’) during the previous day. An estimate of the number of ‘casual contacts’ (i.e. <5 minutes) was also obtained. A total of 568 individuals were included. On average participants reported having routine contact with 7.2 individuals (range 1-25). Children aged 5-14 years had the highest frequency of contacts and the elderly (≥65 years) the fewest (P<0.001). A strong age-assortative pattern was seen, particularly outside the household and increasingly so for contacts occurring further away from home. Adults aged 25-64 years tended to travel more and further than others, and males travelled more frequently than females. Our study provides detailed information on contact patterns and their spatial characteristics in an African setting. It therefore fills an important knowledge gap that will help more accurately predict transmission dynamics and the impact of control strategies in such areas.