PT - JOURNAL ARTICLE AU - Mengbiao Guo AU - Jing Yang AU - Yu lung Lau AU - Wanling Yang TI - RETA: An R package for whole exome and targeted region sequencing data analysis AID - 10.1101/121384 DP - 2017 Jan 01 TA - bioRxiv PG - 121384 4099 - http://biorxiv.org/content/early/2017/03/28/121384.short 4100 - http://biorxiv.org/content/early/2017/03/28/121384.full AB - Whole exome and targeted sequencing have been playing a major role in diagnoses of Mendelian diseases, but analysis of these data involves using many complicated tools and comprehensive understanding of the analysis results is difficult.Here, we report RETA, an R package to provide a one-stop analysis of these data and a comprehensive, interactive and easy-to-understand report with many advanced visualization features. It facilitates clinicians and scientists alike to better analyze and interpret this type of sequencing data for disease diagnoses.Availability and implementation https://github.com/reta-s/reta/releasesContact yangwl{at}hku.hk