@article {Stoeckius113068, author = {Marlon Stoeckius and Christoph Hafemeister and William Stephenson and Brian Houck-Loomis and Harold Swerdlow and Rahul Satija and Peter Smibert}, title = {Large-scale simultaneous measurement of epitopes and transcriptomes in single cells}, elocation-id = {113068}, year = {2017}, doi = {10.1101/113068}, publisher = {Cold Spring Harbor Laboratory}, abstract = {Recent high-throughput single-cell sequencing approaches have been transformative for understanding complex cell populations, but are unable to provide additional phenotypic information, such as protein levels of well-established cell-surface markers. Using oligonucleotide-labeled antibodies, we integrate measurements of cellular proteins and transcriptomes into an efficient, sequencing-based readout of single cells. This method is compatible with existing single-cell sequencing approaches and will readily scale as the throughput of these methods increase.}, URL = {https://www.biorxiv.org/content/early/2017/03/03/113068}, eprint = {https://www.biorxiv.org/content/early/2017/03/03/113068.full.pdf}, journal = {bioRxiv} }