PT - JOURNAL ARTICLE AU - MaurĂ­cio Vieira Kritz TI - Biological Organization, Biological Information, and Knowledge AID - 10.1101/012617 DP - 2014 Jan 01 TA - bioRxiv PG - 012617 4099 - http://biorxiv.org/content/early/2014/12/15/012617.short 4100 - http://biorxiv.org/content/early/2014/12/15/012617.full AB - A concept of information designed to handle information conveyed by organizations is introduced. This concept of information may be used at all biological scales: from molecular and intracellular to multi-cellular organisms and human beings, and further on to collectivities, societies and culture. In this short account, two ground concepts necessary for developing the definition will also be introduced: whole-part graphs, a model for biological organization, and synexions, their immersion into space-time. This definition of information formalizes perception, observers and interpretation; allowing for considering information-exchange as a basic form of biological interaction. Some of its elements will be clarified by arguing and explaining why the immersion of whole-part graphs in (the physical) space-time is needed.