RT Journal Article SR Electronic T1 How much research is spurred when a gene is associated with a complex disease? JF bioRxiv FD Cold Spring Harbor Laboratory SP 106773 DO 10.1101/106773 A1 Travis J. Struck A1 Brian K. Mannakee A1 Ryan N. Gutenkunst YR 2017 UL http://biorxiv.org/content/early/2017/02/07/106773.abstract AB The impact of genome-wide association studies (GWAS) on biomedical research output was quantitatively evaluated. GWAS have not changed the historical skew of publications toward genes involved in Mendelian diseases, but genes newly implicated by GWAS in complex disease do experience a modest increase in publication activity. The impact of GWAS on biomedical research into individual genes is declining, however, even as the rate of new GWAS associations increases.