PT  - JOURNAL ARTICLE
AU  - Travis J. Struck
AU  - Brian K. Mannakee
AU  - Ryan N. Gutenkunst
TI  - How much research is spurred when a gene is associated with a complex disease?
AID  - 10.1101/106773
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 106773
4099  - http://biorxiv.org/content/early/2017/02/07/106773.short
4100  - http://biorxiv.org/content/early/2017/02/07/106773.full
AB  - The impact of genome-wide association studies (GWAS) on biomedical research output was quantitatively evaluated. GWAS have not changed the historical skew of publications toward genes involved in Mendelian diseases, but genes newly implicated by GWAS in complex disease do experience a modest increase in publication activity. The impact of GWAS on biomedical research into individual genes is declining, however, even as the rate of new GWAS associations increases.