RT Journal Article
SR Electronic
T1 Fast Assembling of Neuron Fragments in Serial 3D Sections
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 097253
DO 10.1101/097253
A1 Hanbo Chen
A1 Daniel M. Iascone
A1 Nuno Macarico da Costa
A1 Ed S. Lein
A1 Tianming Liu
A1 Hanchuan Peng
YR 2016
UL http://biorxiv.org/content/early/2016/12/29/097253.abstract
AB Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.