RT Journal Article SR Electronic T1 Cooperative development of logical modelling standards and tools with CoLoMoTo JF bioRxiv FD Cold Spring Harbor Laboratory SP 010504 DO 10.1101/010504 A1 Aurélien Naldi A1 Pedro T. Monteiro A1 Christoph Müssel A1 the Consortium for Logical Models and Tools A1 Hans A. Kestler A1 Denis Thieffry A1 Ioannis Xenarios A1 Julio Saez-Rodriguez A1 Tomas Helikar A1 Claudine Chaouiya YR 2014 UL http://biorxiv.org/content/early/2014/10/19/010504.abstract AB The identification of large regulatory and signalling networks involved in the control of crucial cellular processes calls for proper modelling approaches. Indeed, models can help elucidate properties of these networks, understand their behaviour, and provide (testable) predictions by performing in silico experiments. In this context, qualitative, logical frameworks have emerged as relevant approaches as demonstrated by a growing number of published models, along with new methodologies and software tools. This productive activity now requires a concerted effort to ensure model reusability and interoperability between tools. Here, we outline the logical modelling framework and present the most important achievements of the Consortium for Logical Models and Tools, along with future objectives. This open community welcomes contributions from all researchers interested in logical modelling or in related mathematical and computational developments.