TY - JOUR T1 - A first-principle for the nervous system JF - bioRxiv DO - 10.1101/087353 SP - 087353 AU - Kunjumon I. Vadakkan Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/11/12/087353.abstract N2 - Higher brain functions such as perception and memory are first-person internal sensations whose mechanisms can have options to concurrently activate motor neurons for behavioral action. By setting up all the required constraints using available information from different levels, a theoretical examination from a first-person frame of reference led to the derivation of a first-principle of the structure-function units. These units operate in synchrony with the synaptically-connected neural circuitry. These units are capable of explaining and interconnecting findings from various levels and enable triangulation of a large number of observations from both the normal and “loss of function” states of the system. Indirect evidence for the presence of a comparable circuitry in a remote species − Drosophila − suggests the universal presence of these units across the animal kingdom. The key features of the basic unit meet the expectations of the K-lines proposed for the development of artificial intelligence. ER -