RT Journal Article SR Electronic T1 The Real-time fMRI Neurofeedback Based Stratification of Default Network Regulation Neuroimaging Data Repository JF bioRxiv FD Cold Spring Harbor Laboratory SP 075275 DO 10.1101/075275 A1 Amalia R McDonald A1 Jordan Muraskin A1 Nicholas T Van Dam A1 Caroline Froehlich A1 Benjamin Puccio A1 John Pellman A1 Clemens CC Bauer A1 Alexis Akeyson A1 Melissa M Breland A1 Vince D Calhoun A1 Steven Carter A1 Tiffany P Chang A1 Chelsea Gessner A1 Alyssa Gianonne A1 Steven Giavasis A1 Jamie Glass A1 Steven Homan A1 Margaret King A1 Melissa Kramer A1 Drew Landis A1 Alexis Lieval A1 Jonathan Lisinski A1 Anna Mackay-Brandt A1 Brittny Miller A1 Laura Panek A1 Hayley Reed A1 Christine Santiago A1 Eszter Schoell A1 Richard Sinnig A1 Melissa Sital A1 Elise Taverna A1 Russell Tobe A1 Kristin Trautman A1 Betty Varghese A1 Lauren Walden A1 Runtang Wang A1 Abigail B Waters A1 Dylan Wood A1 F Xavier Castellanos A1 Bennett Leventhal A1 Stanley J Colcombe A1 Stephen LaConte A1 Michael P Milham A1 R Cameron Craddoc YR 2016 UL http://biorxiv.org/content/early/2016/10/31/075275.abstract AB This data descriptor describes a repository of openly shared data from an experiment to assess inter-individual differences in default mode network (DMN) activity. This repository includes cross-sectional functional magnetic resonance imaging (fMRI) data from the Multi Source Interference Task, to assess DMN deactivation, the Moral Dilemma Task, to assess DMN activation, a resting state fMRI scan, and a DMN neurofeedback paradigm, to assess DMN modulation, along with accompanying behavioral and cognitive measures. We report technical validation from n=125 participants of the final targeted sample of 180 participants. Each session includes acquisition of one whole-brain anatomical scan and whole-brain echo-planar imaging (EPI) scans, acquired during the aforementioned tasks and resting state. The data includes several self-report measures related to perseverative thinking, emotion regulation, and imaginative processes, along with a behavioral measure of rapid visual information processing.Technical validation of the data confirms that the tasks deactivate and activate the DMN as expected. Group level analysis of the neurofeedback data indicates that the participants are able to modulate their DMN with considerable inter-subject variability. Preliminary analysis of behavioral responses and specifically self-reported sleep indicate that as many as 73 participants may need to be excluded from an analysis depending on the hypothesis being tested.