RT Journal Article
SR Electronic
T1 The genome of the crustacean <em>Parhyale hawaiensis</em>: a model for animal development, regeneration, immunity and lignocellulose digestion
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 065789
DO 10.1101/065789
A1 Damian Kao
A1 Alvina G. Lai
A1 Evangelia Stamataki
A1 Silvana Rosic
A1 Nikolaos Konstantinides
A1 Erin Jarvis
A1 Alessia Di Donfrancesco
A1 Natalia Pouchkina-Stantcheva
A1 Marie Sémon
A1 Marco Grillo
A1 Heather Bruce
A1 Suyash Kumar
A1 Igor Siwanowicz
A1 Andy Le
A1 Andrew Lemire
A1 Michael B. Eisen
A1 Cassandra Extavour
A1 William E. Browne
A1 Carsten Wolff
A1 Michalis Averof
A1 Nipam H. Patel
A1 Peter Sarkies
A1 Anastasios Pavlopoulos
A1 A. Aziz Aboobaker
YR 2016
UL http://biorxiv.org/content/early/2016/10/13/065789.abstract
AB The amphipod crustacean Parhyale hawaiensis is a blossoming model system for studies of developmental mechanisms and more recently regeneration. We have sequenced the genome allowing annotation of all key signaling pathways, transcription factors, and non-coding RNAs that will enhance ongoing functional studies. Parhyale is a member of the Malacostraca clade, which includes crustacean food crop species. We analysed the immunity related genes of Parhyale as an important comparative system for these species, where immunity related aquaculture problems have increased as farming has intensified. We also find that Parhyale and other species within Multicrustacea contain the enzyme sets necessary to perform lignocellulose digestion (“wood eating”), suggesting this ability may predate the diversification of this lineage. Our data provide an essential resource for further development of Parhyale as an experimental model. The first malacostracan genome will underpin ongoing comparative work in food crop species and research investigating lignocellulose as an energy source.