RT Journal Article
SR Electronic
T1 dbOTU3: A new implementation of distribution-based OTU calling
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 076927
DO 10.1101/076927
A1 Scott Olesen
A1 Claire Duvallet
A1 Eric Alm
YR 2016
UL http://biorxiv.org/content/early/2016/09/22/076927.abstract
AB Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences’ distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers.