PT  - JOURNAL ARTICLE
AU  - Gregory W. Vurture
AU  - Fritz J. Sedlazeck
AU  - Maria Nattestad
AU  - Charles J. Underwood
AU  - Han Fang
AU  - James Gurtowski
AU  - Michael C. Schatz
TI  - GenomeScope: Fast reference-free genome profiling from short reads
AID  - 10.1101/075978
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 075978
4099  - http://biorxiv.org/content/early/2016/09/19/075978.short
4100  - http://biorxiv.org/content/early/2016/09/19/075978.full
AB  - Summary GenomeScope is an open-source web tool to rapidly estimate the overall characteristics of a genome, including genome size, heterozygosity rate, and repeat content from unprocessed short reads. These features are essential for studying genome evolution, and help to choose parameters for downstream analysis. We demonstrate its accuracy on 324 simulated and 16 real datasets with a wide range in genome sizes, heterozygosity levels, and error rates.Availability and Implementation http://qb.cshl.edu/genomescope/, https://github.com/schatzlab/genomescope.gitContact mschatz@jhu.eduSupplementary information Supplementary data are available at Bioinformatics online.