RT Journal Article
SR Electronic
T1 Assessing Prediction Performance of Neoadjuvant Chemotherapy Response in Bladder Cancer
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 075705
DO 10.1101/075705
A1 Chris Cremer
YR 2016
UL http://biorxiv.org/content/early/2016/09/16/075705.abstract
AB Neoadjuvant chemotherapy is a treatment routinely prescribed to patients diagnosed with muscle-invasive bladder cancer. Unfortunately, not all patients are responsive to this treatment and would greatly benefit from an accurate prediction of their expected response to chemotherapy. In this project, I attempt to develop a model that will predict response using tumour microarray data. I show that using my dataset, every method is insufficient at accurately classifying responders and non-responders.