TY - JOUR T1 - Bursting deep dorsal horn neurons: the pharmacological target for the anti-spastic effects of Zolmitriptan? JF - bioRxiv DO - 10.1101/075697 SP - 075697 AU - Eva Meier Carlsen AU - Rune Rasmussen Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/09/16/075697.abstract N2 - In a recent publication, Thaweerattanasinp and colleagues employed an in vitro preparation and electrophysiology to investigate firing properties of deep dorsal horn neurons following spinal cord injury during NMDA or zolmitriptan application. Deep dorsal horn neurons were classified into bursting, simple or tonic, with bursting neurons showing NMDA and zolmitriptan sensitivity. Here, we discuss the findings in a methodological framework and propose future experiments of importance for translating the results into a physiological setting. ER -