PT  - JOURNAL ARTICLE
AU  - Eva Meier Carlsen
AU  - Rune Rasmussen
TI  - Bursting deep dorsal horn neurons: the pharmacological target for the anti-spastic effects of Zolmitriptan?
AID  - 10.1101/075697
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 075697
4099  - http://biorxiv.org/content/early/2016/09/16/075697.short
4100  - http://biorxiv.org/content/early/2016/09/16/075697.full
AB  - In a recent publication, Thaweerattanasinp and colleagues employed an in vitro preparation and electrophysiology to investigate firing properties of deep dorsal horn neurons following spinal cord injury during NMDA or zolmitriptan application. Deep dorsal horn neurons were classified into bursting, simple or tonic, with bursting neurons showing NMDA and zolmitriptan sensitivity. Here, we discuss the findings in a methodological framework and propose future experiments of importance for translating the results into a physiological setting.