TY - JOUR T1 - Biogeographic Ancestry and Socioeconomic Outcomes in the Americas: a Meta-analysis JF - bioRxiv DO - 10.1101/055681 SP - 055681 A2 - , Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/09/12/055681.abstract N2 - Narrative reports suggest that socioeconomic status (SES) is associated with biogeographic ancestry (BGA) in the Americas. If so, SES potentially acts as a confound that needs to be taken into account when evaluating the relation between medical outcomes and BGA. To explore how systematic BGA-SES associations are, a meta-analysis of American studies was conducted. 41 studies were identified, yielding a total of 64 independent samples with directions of associations, including 48 independent samples with effect sizes. An analysis of association directions found a high degree of consistency. The square root n-weighted directions were 0.83 (K = 36), −0.81 (K = 41) and −0.82 (K = 39) for European, Amerindian and African BGA, respectively. An analysis of effect size magnitudes found that European BGA was positively associated with SES, with a meta-analytic effect size of r = .18 [95% CI: .13 to .24, K = 28, n = 35,476.50], while both Amerindian and African BGA were negatively associated with SES, having meta-analytic effect sizes of −.14 [−.18 to −.10, k =31, n = 28,937.50] and −.11 [−.15 to −.07, K = 28, n = 32,710.50], respectively. There was considerable cross-sample variation in effect sizes (mean I2 = 92%), but the sample size was not enough for performing credible moderator analysis. Implications for future studies are discussed. ER -