PT  - JOURNAL ARTICLE
AU  - Joanie Caron
AU  - Gregory R. duManoir
AU  - Lawrence Labrecque
AU  - Audrey Chouinard
AU  - Annie Ferland
AU  - Paul Poirier
AU  - Sylvie Legault
AU  - Patrice Brassard
TI  - Impact of type 2 diabetes on cardiorespiratory function and exercise performance
AID  - 10.1101/073205
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 073205
4099  - http://biorxiv.org/content/early/2016/09/05/073205.short
4100  - http://biorxiv.org/content/early/2016/09/05/073205.full
AB  - The aim of this study was to examine the impact of well-controlled uncomplicated type 2 diabetes (T2D) on exercise performance. Six obese sedentary men with T2D and 7 control participants without diabetes matched for age, sex and body mass index were recruited. Anthropometric characteristics, blood samples, resting cardiac and pulmonary functions and maximal oxygen uptake (VO2max) and ventilatory threshold were measured on a first visit. On the four subsequent visits, participants performed step transitions (6 min) of moderate-intensity exercise on an upright cycle ergometer from unloaded pedaling to 80 % of ventilatory threshold. VO2 (τVO2) and HR (τHR) kinetics were characterized with a mono-exponential model. VO2max (27.8±4.0 vs. 27.5±5.3 ml kg-1 min-1; p=0.95), τVO2 (43±6 vs. 43±10 s; p=0.73) and τHR (42±17 vs. 43±13 s; p=0.94) were similar between diabetics and controls respectively. The remaining variables were also similar between groups. These results suggest that well-controlled T2D is not associated with a reduction in VO2max or slower τVO2 and τHR.