RT Journal Article
SR Electronic
T1 GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 067561
DO 10.1101/067561
A1 Boris Simovski
A1 Daniel Vodak
A1 Sveinung Gundersen
A1 Diana Domanska
A1 Abdulrahman Azab
A1 Lars Holden
A1 Marit Holden
A1 Ivar Grytten
A1 Knut Rand
A1 Finn Drabløs
A1 Morten Johansen
A1 Antonio Mora
A1 Christin Lund-Andersen
A1 Bastian Fromm
A1 Ragnhild Eskeland
A1 Odd Stokke Gabrielsen
A1 Sigve Nakken
A1 Mads Bengtsen
A1 Alexander Johan Nederbragt
A1 Hildur Sif Thorarensen
A1 Johannes Andreas Akse
A1 Ingrid Glad
A1 Eivind Hovig
A1 Geir Kjetil Sandve
YR 2016
UL http://biorxiv.org/content/early/2016/08/03/067561.abstract
AB Genome-wide, cell-type-specific profiles are being systematically generated for numerous genomic and epigenomic features. There is, however, no universally applicable analytical methodology for such data. We present GSuite HyperBrowser, the first comprehensive solution for integrative analysis of dataset collections across the genome and epigenome. The GSuite HyperBrowser is an open-source system for streamlined acquisition and customizable statistical analysis of large collections of genome-wide datasets. The system is based on new computational and statistical methodologies that permit comparative and confirmatory analyses across multiple disparate data sources. Expert guidance and reproducibility are facilitated via a Galaxy-based web-interface. The software is available at https://hyperbrowser.uio.no/gsuiteENCODEThe Encyclopedia of DNA Elements;SNPSingle Nucleotide Polymorphism;TFTranscription Factor;URIUniform Resource Identifier;URLUniform Resource Locator