TY - JOUR T1 - PathScore: a web tool for identifying altered pathways in cancer data JF - bioRxiv DO - 10.1101/067090 SP - 067090 AU - Stephen G. Gaffney AU - Jeffrey P. Townsend Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/08/01/067090.abstract N2 - Summary PathScore quantifies the level of enrichment of somatic mutations within curated pathways, applying a novel approach that identifies pathways enriched across patients. The application provides several user-friendly, interactive graphic interfaces for data exploration, including tools for comparing pathway effect sizes, significance, gene-set overlap and enrichment differences between projects.Availability and Implementation Web application available at pathscore.publichealth.yale.edu. Site implemented in Python and MySQL, with all major browsers supported. Source code available at github.com/sggaffney/pathscore with a GPLv3 license.Contact stephen.gaffney{at}yale.eduSupplementary Information Additional documentation can be found at http://pathscore.publichealth.yale.edu/faq. ER -