PT  - JOURNAL ARTICLE
AU  - Lars Feuerbach
AU  - Lina Sieverling
AU  - Katharina I. Deeg
AU  - Philip Ginsbach
AU  - Barbara Hutter
AU  - Ivo Buchhalter
AU  - Paul A. Northcott
AU  - Peter Lichter
AU  - Stefan M. Pfister
AU  - David T.W. Jones
AU  - Karsten Rippe
AU  - Benedikt Brors
TI  - TelomereHunter: telomere content estimation and characterization from whole genome sequencing data
AID  - 10.1101/065532
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 065532
4099  - http://biorxiv.org/content/early/2016/07/23/065532.short
4100  - http://biorxiv.org/content/early/2016/07/23/065532.full
AB  - Summary: Telomere shortening plays an important role in cellular aging and tumor suppression. The availability of large next-generation sequencing cohorts of matched tumor and control samples enables a computational high-throughput analysis of changes in telomere content and composition in cancer. Here we describe a novel software tool specifically tailored for the processing of large data collections.Availability and Implementation: TelomereHunter is implemented as a python package. It is freely available online at: http://www.dkfz.de/en/applied-bioinformatics/telomerehunter/telomerehunter.html.