PT  - JOURNAL ARTICLE
AU  - Bohdan B. Khomtchouk
AU  - James R. Hennessy
AU  - Claes Wahlestedt
TI  - MicroScope: ChIP-seq and RNA-seq software analysis suite for gene expression heatmaps
AID  - 10.1101/034694
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 034694
4099  - http://biorxiv.org/content/early/2016/07/04/034694.short
4100  - http://biorxiv.org/content/early/2016/07/04/034694.full
AB  - We propose a user-friendly ChIP-seq and RNA-seq software suite for the interactive visualization and analysis of genomic data, including integrated features to support differential expression analysis, interactive heatmap production, principal component analysis, gene ontology analysis, and dynamic network analysis.MicroScope is hosted online as an R Shiny web application based on the D3 JavaScript library: http://microscopebioinformatics.org/. The methods are implemented in R, and are available as part of the MicroScope project at: https://github.com/Bohdan-Khomtchouk/Microscope.FDRfalse discovery rateGOgene ontologyUIuser interfacePCAprincipal component analysisDEdifferential expressionqCMLquantile-adjusted conditional maximum likelihood