@article {Wang057885, author = {Bin Wang and Ni Ye and San-jie Cao and Xin-tian Wen and Yongxs Huang and Qi-gui Yan}, title = {Identification of Novel and Differentially Expressed MicroRNAs in Goat Enzootic Nasal Adenocarcinoma}, elocation-id = {057885}, year = {2016}, doi = {10.1101/057885}, publisher = {Cold Spring Harbor Laboratory}, abstract = {Enzootic nasal adenocarcinoma (ENA), an epithelial tumor induced in goats and sheep by enzootic nasal tumor virus (ENTV), is a chronic, progressive,contact transmitted disease. This study aimed to identify novel and differentially expressed miRNAs in the tumor and para-carcinoma nasal tissuesofNanjiang yellow goats with ENA. Small RNA Illumina high-throughput sequencing was used to construct a goat nasal miRNA library.406 known miRNAs and 29 novel miRNAs were identified. A total of 116 miRNAs were significantly differentially expressed in para-carcinoma nasal tissues and ENA; Target gene prediction and functional analysis revealed that 6176 non-redundancy target genes, 1792 significant GO and 97 significant KEGG pathway for 121 miRNAs were predicted.}, URL = {https://www.biorxiv.org/content/early/2016/06/08/057885}, eprint = {https://www.biorxiv.org/content/early/2016/06/08/057885.full.pdf}, journal = {bioRxiv} }