RT Journal Article
SR Electronic
T1 MicroScope: ChIP-seq and RNA-seq software analysis suite for gene expression heatmaps
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 034694
DO 10.1101/034694
A1 Bohdan B. Khomtchouk
A1 James R. Hennessy
A1 Vytas Dargis-Robinson
A1 Claes Wahlestedt
YR 2016
UL http://biorxiv.org/content/early/2016/05/30/034694.abstract
AB We propose a user-friendly ChIP-seq and RNA-seq software suite for the interactive visualization and analysis of gene expression heatmaps, including integrated features to support: principal component analysis, differential expression analysis, gene ontology analysis, and dynamic network visualization of genes directly from a heatmap.MicroScope is hosted online as an R Shiny web application based on the D3 JavaScript library: http://microscopebioinformatics.org/. The methods are implemented in R, and are available as part of the MicroScope project at: https://github.com/Bohdan-Khomtchouk/Microscope.FDRfalse discovery rateGOgene ontologyUIuser interfacePCAprincipal component analysisDEdifferential expression