PT  - JOURNAL ARTICLE
AU  - Bohdan B. Khomtchouk
AU  - James R. Hennessy
AU  - Vytas Dargis-Robinson
AU  - Claes Wahlestedt
TI  - MicroScope: ChIP-seq and RNA-seq software analysis suite for gene expression heatmaps
AID  - 10.1101/034694
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 034694
4099  - http://biorxiv.org/content/early/2016/05/30/034694.short
4100  - http://biorxiv.org/content/early/2016/05/30/034694.full
AB  - We propose a user-friendly ChIP-seq and RNA-seq software suite for the interactive visualization and analysis of gene expression heatmaps, including integrated features to support: principal component analysis, differential expression analysis, gene ontology analysis, and dynamic network visualization of genes directly from a heatmap.MicroScope is hosted online as an R Shiny web application based on the D3 JavaScript library: http://microscopebioinformatics.org/. The methods are implemented in R, and are available as part of the MicroScope project at: https://github.com/Bohdan-Khomtchouk/Microscope.FDRfalse discovery rateGOgene ontologyUIuser interfacePCAprincipal component analysisDEdifferential expression