PT  - JOURNAL ARTICLE
AU  - Timothy K. Leonard
AU  - Kari L. Hoffman
TI  - Experience-dependent increases in sharp-wave ripples near visual targets
AID  - 10.1101/054171
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 054171
4099  - http://biorxiv.org/content/early/2016/05/18/054171.short
4100  - http://biorxiv.org/content/early/2016/05/18/054171.full
AB  - We measured hippocampal sharp-wave ripples during goal-directed visual exploration in macaques. Exploratory sharp-wave ripples were more frequent on familiar trials, in the second half of search, and near the visual target (i.e., the goal location). These spatial and temporal properties may help SWRs coordinate hippocampal and extra-hippocampal firing sequences that guide actions based on past experiences.