RT Journal Article SR Electronic T1 plasmidSPAdes: Assembling Plasmids from Whole Genome Sequencing Data JF bioRxiv FD Cold Spring Harbor Laboratory SP 048942 DO 10.1101/048942 A1 Dmitry Antipov A1 Nolan Hartwick A1 Max Shen A1 Mikhail Raiko A1 Alla Lapidus A1 Pavel A. Pevzner YR 2016 UL http://biorxiv.org/content/early/2016/04/17/048942.abstract AB Motivation Plasmids are stably maintained extra-chromosomal genetic elements that replicate independently from the host cell’s chromosomes. Although plasmids harbor biomedically important genes, (such as genes involved in virulence and antibiotics resistance), there is a shortage of specialized software tools for extracting and assembling plasmid data from whole genome sequencing projects.Results We present the plasmidSPAdes algorithm and software tool for assembling plasmids from whole genome sequencing data and benchmark its performance on a diverse set of bacterial genomes.Availability and implementation PLASMIDSPADES is publicly available at http://spades.bioinf.spbau.ru/plasmidSPAdes/Contact d.antipov{at}spbu.ru