RT Journal Article SR Electronic T1 Drosophila Mutants that Are Motile but Respond Poorly to All Stimuli Tested JF bioRxiv FD Cold Spring Harbor Laboratory SP 045062 DO 10.1101/045062 A1 Lar L. Vang A1 Julius Adler YR 2016 UL http://biorxiv.org/content/early/2016/04/12/045062.abstract AB Adult Drosophila melanogaster fruit flies were placed into one end of a tube near to repellents (benzaldehyde and heat) and away from the other end containing attractants (light and a favored temperature). They escaped from the repellents and went to the attractants. Motile mutants that failed to do that were isolated. They did not respond to any external attractants tested or external repellents tested. In addition, they did not respond well to internal stimuli like hunger, thirst, and sleep. Some possibilities for explaining the deficiency: They may be defective in decision making that results from faulty interaction with the sensing mechanism, or they may be defective in executive function. The mutants failed at both 34°C and, in one case studied, at room temperature.