RT Journal Article
SR Electronic
T1 diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 005082
DO 10.1101/005082
A1 Paula Tataru
A1 Jasmine A. Nirody
A1 Yun S. Song
YR 2014
UL http://biorxiv.org/content/early/2014/05/13/005082.abstract
AB Summary We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing IBD detection methods, while retaining reasonable accuracy for IBD tracts as small as 0.1 cM.Availability http://sourceforge.net/p/dical-ibdContact yss@eecs.berkeley.edu