TY - JOUR T1 - NanoSim: nanopore sequence read simulator based on statistical characterization JF - bioRxiv DO - 10.1101/044545 SP - 044545 AU - Chen Yang AU - Justin Chu AU - René L Warren AU - Inanç Birol Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/03/18/044545.1.abstract N2 - Motivation: In 2014, Oxford Nanopore Technologies (ONT) announced a new sequencing platform called MinION. The particular features of MinION reads – longer read lengths and single-molecule sequencing in particular – show potential for genome characterization. As of yet, the pre-commercial technology is exclusively available through early-access, and only a few datasets are publically available for testing. Further, no software exists that simulates MinION platform reads with genuine ONT characteristics.Results: In this article, we introduce NanoSim, a fast and scalable read simulator that captures the technology-specific features of ONT data, and allows for adjustments upon improvement of nanopore sequencing technology. ER -