PT - JOURNAL ARTICLE AU - Daryl Waggott AU - Euan Ashley AU - Anja Bog AU - Enakshi Singh AU - Anil Ankisettipalli AU - Surbhi Sheth-Shah AU - Dianna Fisk AU - Anna Shcherbina AU - Megan Grove AU - Prag Batra AU - Mark H. Wright AU - Matthew Wheeler AU - Jason Merker AU - Werner Eberhardt AU - Carlos D. Bustamante TI - The Next Generation Precision Medical Record - A Framework for Integrating Genomes and Wearable Sensors with Medical Records AID - 10.1101/039651 DP - 2016 Jan 01 TA - bioRxiv PG - 039651 4099 - http://biorxiv.org/content/early/2016/02/21/039651.short 4100 - http://biorxiv.org/content/early/2016/02/21/039651.full AB - Current medical records are rigid with regards to emerging big biomedical data. Examples of poorly integrated big data that already exist in clinical practice include whole genome sequencing and wearable sensors for real time monitoring. Genome sequencing enables conventional diagnostic interrogation and forms the fundamental baseline for precision health throughout out a patient’s lifetime. Mobile sensors enable tailored monitoring regimes for both reducing risk through precision health interventions and acute condition surveillance.In order to address the absence of these data in the Electronic Medical Record (EMR), we worked with SAP Healthcare to reenvision a modern medical record with these components. The pilot project used 37 patient families with complex medical records, whole genome sequencing and some level of wearable monitoring. Core functionality include patient timelines with integrated text analytics, personalized genomic curation and wearable alerts. The current phase is being rolled out to over 1500 patients in clinics across the hospital system. While fundamentally research, we believe this proof of principle platform is the first of its kind and represents the future of data driven clinical medicine.