RT Journal Article
SR Electronic
T1 Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 040477
DO 10.1101/040477
A1 Po-E Li
A1 Chien-Chi Lo
A1 Joseph J. Anderson
A1 Karen W. Davenport
A1 Kimberly A. Bishop-Lilly
A1 Yan Xu
A1 Sanaa Ahmed
A1 Shihai Feng
A1 Vishwesh P. Mokashi
A1 Patrick S. G. Chain
YR 2016
UL http://biorxiv.org/content/early/2016/02/21/040477.abstract
AB Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools. These preconfigured workflows provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks, and, within the context of the same environment, to visualize and further interrogate their results. This bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications.