TY - JOUR T1 - Response to “Commentary on ‘Limitations of GCTA as a solution to the missing heritability problem” JF - bioRxiv DO - 10.1101/039594 SP - 039594 AU - Siddharth Krishna Kumar AU - Marcus W. Feldman AU - David H. Rehkopf AU - Shripad Tuljapurkar Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/02/17/039594.abstract N2 - In a recent manuscript [18], Yang and colleagues criticized our paper, ‘Limitations of GCTA as a solution to the missing heritability problem’ [9]. Henceforth we refer to our original paper as SK and the critique as YC.Here we show that their main claims are statistically invalid. We begin with an overview and the mathematical details follow in subsequent sections. ER -