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History
- April 20, 2017.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Author Information
- Miten Jain1,§,
- S Koren2,§,
- J Quick3,§,
- AC Rand1,§,
- TA Sasani4,5,§,
- JR Tyson7,§,
- AD Beggs8,
- AT Dilthey2,
- IT Fiddes1,
- S Malla9,
- H Marriott9,
- KH Miga1,
- T Nieto8,
- J O’Grady10,
- HE Olsen1,
- BS Pedersen4,5,
- A Rhie2,
- H Richardson10,
- AR Quinlan4,5,6,
- TP Snutch7,
- L Tee8,
- B Paten1,
- AM Phillippy2,
- JT Simpson11,12,
- NJ Loman3,* and
- M Loose9,*
- 1UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
- 2Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, Maryland, USA
- 3Institute of Microbiology and Infection, University of Birmingham, Birmingham B15 2TT, UK
- 4Department of Human Genetics, University of Utah, Salt Lake City, UT, USA
- 5USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, UT, USA
- 6Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA
- 7Michael Smith Laboratories and Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, Canada
- 8Surgical Research Laboratory, Institute of Cancer & Genomic Science, University of Birmingham, UK
- 9DeepSeq, School of Life Sciences, University of Nottingham, UK
- 10Norwich Medical School, University of East Anglia, Norwich, UK
- 11Ontario Institute for Cancer Research, Toronto M5G 0A3, Canada
- 12Department of Computer Science, University of Toronto, Toronto M5S 3G4, Canada
- ↵*Authors for correspondence n.j.loman{at}bham.ac.uk, matt.loose{at}nottingham.ac.uk
↵§ These authors contributed equally to this work.
Contributions: N.J.L, M.L, J.T.S, and J.R.T conceived the study, J.Q developed the long read protocol, A.D.B, M.J, M.L, H.M, S.M, T.N, J.O’G, J.Q, H.R, J.R.T and L.T prepared materials and/or performed sequencing, A.T.D, I.T.F, M.J, S.K, N.J.L, M.L, K.H.M, H.E.O, B.P, B.S.P, A.M.P, A.R.Q, A.C.R, A.R, T.A.S, J.T.S and J.R.T performed bioinformatics analysis and wrote or modified software, I.T.F, M.J, S.K, N.J.L, M.L, K.H.M, J.O’G, H.E.O, B.P, A.M.P, J.Q, A.R.Q, A.C.R, T.A.S, J.T.S, T.P.S and J.R.T wrote and edited the manuscript. All authors approved the manuscript and provided strategic oversight for the work.