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History
- November 25, 2016.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Author Information
- Tyler M. Seibert, MD1,2,
- Chun Chieh Fan, MD1,3,
- Yunpeng Wang, PhD4,
- Verena Zuber, PhD4,
- Roshan Karunamuni, PhD1,2,
- J. Kellogg Parsons, MD5,
- Rosalind A. Eeles, PhD6,7,
- Douglas F. Easton, PhD8,
- ZSofia Kote-Jarai, PhD6,
- Ali Amin Al Olama, PhD8,
- Sara Benlloch Garcia, PhD8,
- Kenneth Muir, PhD9,10,
- Henrik Gronberg, Prof11,
- Fredrik Wiklund, PhD11,
- Markus Aly, PhD11,12,
- Johanna Schleutker, PhD13,14,
- Csilla Sipeky, PhD15,
- Teuvo LJ Tammela, Prof16,
- Børge G. Nordestgaard, Prof17,18,
- Sune F. Nielsen, PhD17,18,
- Maren Weischer, MD18,
- Rasmus Bisbjerg, MD19,
- M. Andreas Røder, MD20,
- Peter Iversen, Prof17,20,
- Tim J. Key, DPhil21,
- Ruth C. Travis, DPhil21,
- David E. Neal, FMedSci22,23,
- Jenny L. Donovan, PhD24,
- Freddie C. Hamdy, FMedSci25,
- Paul Pharoah, Prof26,
- Nora Pashayan, MD27,26,
- Kay-Tee Khaw, FRCP28,
- Christiane Maier, PhD29,
- Walther Vogel, Prof29,
- Manuel Luedeke, PhD29,
- Kathleen Herkommer, MD30,
- Adam S. Kibel, MD31,
- Cezary Cybulski, MD32,
- Dominika Wokolorczyk, PhD32,
- Wojciech Kluzniak, MS32,
- Lisa Cannon-Albright, PhD33,34,
- Hermann Brenner, Prof35,36,37,
- Katarina Cuk, PhD35,
- Kai-Uwe Saum, PhD35,
- Jong Y. Park, PhD38,
- Thomas A. Sellers, PhD39,
- Chavdar Slavov, DMSc40,
- Radka Kaneva, PhD41,
- Vanio Mitev, DSc41,
- Jyotsna Batra, PhD42,
- Judith A. Clements, PhD42,
- Amanda Spurdle, PhD43,
- Australian Prostate Cancer BioResource42,44,
- Manuel R. Teixeira, PhD45,46,
- Paula Paulo, PhD45,
- Sofia Maia, PhD45,
- Hardev Pandha, FRCP47,
- Agnieszka Michael, PhD47,
- Andrzej Kierzek, PhD47,
- David S. Karow, MD1,48,
- Ian G. Mills, PhD4,49,
- Ole A. Andreassen, MD4,
- Anders M. Dale, PhD1,48,50,
- The PRACTICAL consortium*
- 1Center for Multimodal Imaging & Genetics, University of California, San Diego, La Jolla, CA, USA
- 2Department of Radiation Medicine & Applied Sciences, University of California, San Diego, La Jolla, CA, USA
- 3Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA
- 4University of Oslo, Oslo, Norway
- 5Department of Surgery, University of California, San Diego, La Jolla, CA, USA
- 6The Institute of Cancer Research, London, SM2 5NG, UK
- 7Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK
- 8Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
- 9Institute of Population Health, University of Manchester, Manchester, UK
- 10Warwick Medical School, University of Warwick, Coventry, UK
- 11Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
- 12Department of Molecular Medicine and Surgery, Karolinska Institutet, and Department of Urology, Karolinska University Hospital, Solna, 171 76 Stockholm
- 13Department of Medical Biochemistry and Genetics, Institute of Biomedicine, Kiinamyllynkatu 10, FI-20014 University of Turku; and Tyks Microbiology and Genetics, Department of Medical Genetics, Turku University Hospital
- 14BioMediTech, 30014 University of Tampere, Tampere, Finland
- 15Department of Medical Biochemistry and Genetics, Institute of Biomedicine, Kiinamyllynkatu 10, FI-20014 University of Turku, Finland
- 16Department of Urology, Tampere University Hospital and Medical School, University of Tampere, Finland
- 17Faculty of Health and Medical Sciences, University of Copenhagen, Denmark
- 18Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark
- 19Department of Urology, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark
- 20Copenhagen Prostate Cancer Center, Department of Urology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
- 21Cancer Epidemiology, Nuffield Department of Population Health University of Oxford, Oxford, OX3 7LF, UK
- 22Nuffield Department of Surgery, University of Oxford, Room 6603, Level 6, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK
- 23University of Cambridge, Department of Oncology, Box 279, Addenbrooke’s Hospital, Hills Road Cambridge CB2 0QQ, UK
- 24School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, UK
- 25Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK, Faculty of Medical Science, University of Oxford, John Radcliffe Hospital, Oxford, UK
- 26Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, UK
- 27University College London, Department of Applied Health Research, 1-19 Torrington Place, London, WC1E 7HB
- 28Clinical Gerontology Unit, University of Cambridge, Cambridge UK
- 29Institute of Human Genetics, University Hospital of Ulm, Ulm, Germany
- 30Department of Urology, Klinikum rechts der Isar der Technischen Universitaet Muenchen, Munich, Germany
- 31Division of Urologic Surgery, Brigham and Womens Hospital, Dana-Farber Cancer Institute, 75 Francis Street, Boston, MA 02115, USA
- 32International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland
- 33Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
- 34George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, US
- 35Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany
- 36Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany
- 37German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany
- 38Department of Cancer Epidemiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
- 39Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
- 40Department of Urology and Alexandrovska University Hospital, Medical University, Sofia, Bulgaria
- 41Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University, Sofia, 2 Zdrave Str., 1431 Sofia, Bulgaria
- 42Australian Prostate Cancer Research Centre-Qld, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Australia
- 43Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia
- 44Australian Prostate Cancer BioResource, Institute of Health and Biomedical Innovation and School of Biomedical Science, Queensland University of Technology, Brisbane, Australia
- 45Department of Genetics, Portuguese Oncology Institute, Porto, Portugal
- 46Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal
- 47The University of Surrey, Guildford, Surrey, GU2 7XH
- 48Department of Radiology, University of California, San Diego, La Jolla, CA, USA
- 49Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, UK
- 50Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA
- Corresponding authors Tyler M. Seibert, MD, PhD Center for Multimodal Imaging & Genetics Rm/Bldg: 4W102-B11 / Altman Building UC San Diego Campus Direct 9500 Gilman Drive La Jolla, CA 92093 United States tseibert{at}ucsd.edu (858) 255-1458 Anders M. Dale, PhD Center for Multimodal Imaging & Genetics Rm/Bldg: 4W228 / Altman Building UC San Diego Campus Direct 9500 Gilman Drive La Jolla, CA 92093 United States amdale{at}ucsd.edu (858) 822-6671