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History
- October 25, 2016.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Author Information
- Nathanael G. Lintner1‡,
- Kim F. McClure2a,
- Donna Petersen3,
- Allyn T. Londregan2b,
- David W. Piotrowski2b,
- Liuqing Wei2b,
- Jun Xiao2b,
- Michael Bolt4,
- Paula M. Loria3,
- Bruce Maguire3,
- Kieran F. Geoghegan5,
- Austin Huang6,
- Tim Rolph7,
- Spiros Liras2a,2b,
- Jennifer A. Doudna1,8,9,10,11,
- Robert G. Dullea7,* and
- Jamie H.D. Cate1,8,9,10,*
- 1Department of Molecular and Cell Biology, University of California, Berkeley, California, 94720, USA.
- 2aPfizer Medicinal Chemistry Cardiovascular Metabolic and Endocrine Disease Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts, 02139, USA.
- 2bPfizer Medicinal Chemistry, Cardiovascular, Metabolic and Endocrine Disease Research Unit, Pfizer Worldwide Research and Development, Groton, Connecticut, 06340, USA.
- 3Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut, 06340, USA.
- 4Drug Safety Research & Development, Pfizer Worldwide Research & Development, Andover, Massachusetts, 01810 USA.
- 5Pfizer Medicinal Chemistry Structural Biology and Biophysics Pfizer Worldwide Research and Development, Groton, Connecticut, 06340, USA.
- 6Pfizer Medicinal Chemistry, Computational Sciences, Pfizer Worldwide Research and Development, Cambridge, Massachusetts, 02139, USA.
- 7Cardiovascular, Metabolic and Endocrine Disease Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts, 02139, USA.
- 8QB3 Institute, University of California, Berkeley, California, 94720, USA.
- 9Department of Chemistry, University of California, Berkeley, California, 94720, USA.
- 10Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, 94720, USA.
- 11Howard Hughes Medical Institute (HHMI) University of California, Berkeley, California, 94720, USA.
- ↵∗Correspondence should be addressed to R.G.D (robert.dullea{at}pfizer.com) or J.H.D.C. (jcate{at}lbl.gov).