Identifying species threat hotspots has been a successful approach for setting conservation priorities. One major challenge in conservation is that in many hotspots export industries continue to drive overexploitation. Conservation measures must consider not just the point of impact, but also the consumer demand that ultimately drives resource use. To understand which species threat hotspots are driven by which consumers, we have developed a new approach to link a set of biodiversity footprint accounts to the hotspots of threatened species on the IUCN Red List. The result is a map connecting global supply chains to impact locations. Connecting consumption to spatially explicit hotspots driven by production has not been done before on a global scale. Locating biodiversity threat hotspots driven by consumption of goods and services can help connect conservationists, consumers, companies, and governments in order to better target conservation actions.