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Choice of reference genome can introduce massive bias in bisulfite sequencing data
Phillip Wulfridge, View ORCID ProfileBen Langmead, Andrew P. Feinberg, View ORCID ProfileKasper D. Hansen
doi: https://doi.org/10.1101/076844
Phillip Wulfridge
1Center for Epigenetics, Johns Hopkins School of Medicine
Ben Langmead
2Center for Computational Biology, Johns Hopkins University
3Department of Computer Science, Johns Hopkins University
Andrew P. Feinberg
1Center for Epigenetics, Johns Hopkins School of Medicine
4Department of Medicine, Johns Hopkins School of Medicine
5Department of Biomedical Engineering, Whiting School of Engineering
6Department of Mental Health, Johns Hopkins Bloomberg School of Public Health
Kasper D. Hansen
1Center for Epigenetics, Johns Hopkins School of Medicine
2Center for Computational Biology, Johns Hopkins University
7Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
8McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine
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Posted September 22, 2016.
Choice of reference genome can introduce massive bias in bisulfite sequencing data
Phillip Wulfridge, Ben Langmead, Andrew P. Feinberg, Kasper D. Hansen
bioRxiv 076844; doi: https://doi.org/10.1101/076844
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