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Quantifying the extent to which index event biases influence large genetic association studies
Hanieh Yaghootkar, Michael P. Bancks, Sam E. Jones, Aaron McDaid, Robin Beaumont, Louise Donnelly, Andrew R. Wood, Archie Campbell, Jessica Tyrrell, Lynne J. Hocking, Marcus A. Tuke, Katherine S. Ruth, Ewan R. Pearson, Anna Murray, Rachel M. Freathy, Patricia B. Munroe, Caroline Hayward, Colin Palmer, Michael N. Weedon, James S. Pankow, Timothy M. Frayling, Zoltán Kutalik
doi: https://doi.org/10.1101/074781
Hanieh Yaghootkar
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Michael P. Bancks
2Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, U.S.A.
Sam E. Jones
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Aaron McDaid
3Institute of Social and Preventive Medicine, Lausanne University Hospital, 1010, Switzerland.
4Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.
Robin Beaumont
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Louise Donnelly
5Division of Cardiovascular & Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, Scotland, U.K.
Andrew R. Wood
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Archie Campbell
6Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, U.K.
Jessica Tyrrell
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Lynne J. Hocking
7Institute of Medical Sciences, University of Aberdeen, Aberdeen, U.K.
Marcus A. Tuke
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Katherine S. Ruth
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Ewan R. Pearson
5Division of Cardiovascular & Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, Scotland, U.K.
Anna Murray
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Rachel M. Freathy
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Patricia B. Munroe
8Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, U.K.
9NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine, Queen Mary University of London, London, U.K.
Caroline Hayward
10Generation Scotland, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, U.K.
Colin Palmer
5Division of Cardiovascular & Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, Scotland, U.K.
Michael N. Weedon
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
James S. Pankow
2Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, U.S.A.
Timothy M. Frayling
1Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, U.K.
Zoltán Kutalik
3Institute of Social and Preventive Medicine, Lausanne University Hospital, 1010, Switzerland.
4Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.
Article usage
Posted September 12, 2016.
Quantifying the extent to which index event biases influence large genetic association studies
Hanieh Yaghootkar, Michael P. Bancks, Sam E. Jones, Aaron McDaid, Robin Beaumont, Louise Donnelly, Andrew R. Wood, Archie Campbell, Jessica Tyrrell, Lynne J. Hocking, Marcus A. Tuke, Katherine S. Ruth, Ewan R. Pearson, Anna Murray, Rachel M. Freathy, Patricia B. Munroe, Caroline Hayward, Colin Palmer, Michael N. Weedon, James S. Pankow, Timothy M. Frayling, Zoltán Kutalik
bioRxiv 074781; doi: https://doi.org/10.1101/074781
Quantifying the extent to which index event biases influence large genetic association studies
Hanieh Yaghootkar, Michael P. Bancks, Sam E. Jones, Aaron McDaid, Robin Beaumont, Louise Donnelly, Andrew R. Wood, Archie Campbell, Jessica Tyrrell, Lynne J. Hocking, Marcus A. Tuke, Katherine S. Ruth, Ewan R. Pearson, Anna Murray, Rachel M. Freathy, Patricia B. Munroe, Caroline Hayward, Colin Palmer, Michael N. Weedon, James S. Pankow, Timothy M. Frayling, Zoltán Kutalik
bioRxiv 074781; doi: https://doi.org/10.1101/074781
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