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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Alexander Gusev, Nick Mancuso, Hilary K Finucane, Yakir Reshef, Lingyun Song, Alexias Safi, Edwin Oh, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Steven McCarroll, Benjamin Neale, Roel Ophoff, Michael C O’Donovan, Nicholas Katsanis, Gregory E Crawford, Patrick F Sullivan, Bogdan Pasaniuc, Alkes L Price
doi: https://doi.org/10.1101/067355
Alexander Gusev
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Nick Mancuso
3David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
Hilary K Finucane
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
4Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
Yakir Reshef
5Department of Computer Science, Harvard University, Cambridge, Massachusetts, USA
Lingyun Song
6Center for Genomic and Computational Biology, Duke University, Durham, North Carolina, USA
7Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, North Carolina, USA
Alexias Safi
6Center for Genomic and Computational Biology, Duke University, Durham, North Carolina, USA
7Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, North Carolina, USA
Edwin Oh
8Center for Human Disease Modeling, Duke University Medical Center, Durham, North Carolina, United States
Steven McCarroll
9Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
10Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Benjamin Neale
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
10Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
11Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Roel Ophoff
12Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, California, USA
13Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands
Michael C O’Donovan
14MRC Centre for Psychiatric Genetics and Genomics, Cardiff University, Cardiff, UK
Nicholas Katsanis
8Center for Human Disease Modeling, Duke University Medical Center, Durham, North Carolina, United States
Gregory E Crawford
6Center for Genomic and Computational Biology, Duke University, Durham, North Carolina, USA
7Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, North Carolina, USA
Patrick F Sullivan
15Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, North Carolina, USA
16Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Bogdan Pasaniuc
3David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
Alkes L Price
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Article usage
Posted August 02, 2016.
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Alexander Gusev, Nick Mancuso, Hilary K Finucane, Yakir Reshef, Lingyun Song, Alexias Safi, Edwin Oh, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Steven McCarroll, Benjamin Neale, Roel Ophoff, Michael C O’Donovan, Nicholas Katsanis, Gregory E Crawford, Patrick F Sullivan, Bogdan Pasaniuc, Alkes L Price
bioRxiv 067355; doi: https://doi.org/10.1101/067355
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Alexander Gusev, Nick Mancuso, Hilary K Finucane, Yakir Reshef, Lingyun Song, Alexias Safi, Edwin Oh, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Steven McCarroll, Benjamin Neale, Roel Ophoff, Michael C O’Donovan, Nicholas Katsanis, Gregory E Crawford, Patrick F Sullivan, Bogdan Pasaniuc, Alkes L Price
bioRxiv 067355; doi: https://doi.org/10.1101/067355
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