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Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de Lange, Loukas Moutsianas, James C. Lee, Christopher A. Lamb, Yang Luo, Nicholas A. Kennedy, Luke Jostins, Daniel L. Rice, Javier Gutierrez-Achury, Sun-Gou Ji, Graham Heap, Elaine R. Nimmo, Cathryn Edwards, Paul Henderson, Craig Mowat, Jeremy Sanderson, Jack Satsangi, Alison Simmons, David C. Wilson, Mark Tremelling, Ailsa Hart, Christopher G. Mathew, William G. Newman, Miles Parkes, Charlie W. Lees, Holm Uhlig, Chris Hawkey, Natalie J. Prescott, Tariq Ahmad, John C. Mansfield, Carl A. Anderson, Jeffrey C. Barrett
doi: https://doi.org/10.1101/058255
Katrina M. de Lange
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Loukas Moutsianas
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
James C. Lee
2Inflammatory Bowel Disease Research Group, Addenbrooke’s Hospital, Cambridge, UK
Christopher A. Lamb
3Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne
Yang Luo
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
4Division of Genetics and Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
5Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA
Nicholas A. Kennedy
6Precision Medicine Exeter, University of Exeter, Exeter, UK
7IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK
Luke Jostins
8Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK
9Christ Church, University of Oxford, St Aldates, UK
Daniel L. Rice
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Javier Gutierrez-Achury
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Sun-Gou Ji
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Graham Heap
6Precision Medicine Exeter, University of Exeter, Exeter, UK
7IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK
Elaine R. Nimmo
10Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK
Cathryn Edwards
11Department of Gastroenterology, Torbay Hospital, Torbay, Devon, UK
Paul Henderson
12Department of Child Life and Health, University of Edinburgh, Edinburgh, UK
13Department of Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK
Craig Mowat
14Department of Medicine, Ninewells Hospital and Medical School, Dundee, UK
Jeremy Sanderson
15Guy’s & St Thomas’ NHS Foundation Trust, St Thomas’ Hospital, Department of Gastroenterology, London, UK
Jack Satsangi
10Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK
Alison Simmons
16Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK
17Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK
David C. Wilson
18Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK
19Child Life and Health, University of Edinburgh, Edinburgh, Scotland, UK
Mark Tremelling
20Gastroenterology & General Medicine, Norfolk and Norwich University Hospital, Norwich, UK
Ailsa Hart
21Department of Medicine, St Mark’s Hospital, Harrow, Middlesex, UK
Christopher G. Mathew
22Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King’s College London, Guy’s Hospital, London, UK
23Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa
William G. Newman
24Genetic Medicine, Manchester Academic Health Science Centre, Manchester, UK
25The Manchester Centre for Genomic Medicine, University of Manchester, Manchester, UK
Miles Parkes
2Inflammatory Bowel Disease Research Group, Addenbrooke’s Hospital, Cambridge, UK
Charlie W. Lees
10Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK
Holm Uhlig
26Translational Gastroenterology Unit and the Department of Paediatrics, University of Oxford, Oxford, United Kingdom
Chris Hawkey
27Nottingham Digestive Diseases Centre, Queens Medical Centre, Nottingham, UK
Natalie J. Prescott
22Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King’s College London, Guy’s Hospital, London, UK
Tariq Ahmad
6Precision Medicine Exeter, University of Exeter, Exeter, UK
7IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK
John C. Mansfield
28Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK
Carl A. Anderson
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Jeffrey C. Barrett
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Article usage
Posted June 10, 2016.
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de Lange, Loukas Moutsianas, James C. Lee, Christopher A. Lamb, Yang Luo, Nicholas A. Kennedy, Luke Jostins, Daniel L. Rice, Javier Gutierrez-Achury, Sun-Gou Ji, Graham Heap, Elaine R. Nimmo, Cathryn Edwards, Paul Henderson, Craig Mowat, Jeremy Sanderson, Jack Satsangi, Alison Simmons, David C. Wilson, Mark Tremelling, Ailsa Hart, Christopher G. Mathew, William G. Newman, Miles Parkes, Charlie W. Lees, Holm Uhlig, Chris Hawkey, Natalie J. Prescott, Tariq Ahmad, John C. Mansfield, Carl A. Anderson, Jeffrey C. Barrett
bioRxiv 058255; doi: https://doi.org/10.1101/058255
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Katrina M. de Lange, Loukas Moutsianas, James C. Lee, Christopher A. Lamb, Yang Luo, Nicholas A. Kennedy, Luke Jostins, Daniel L. Rice, Javier Gutierrez-Achury, Sun-Gou Ji, Graham Heap, Elaine R. Nimmo, Cathryn Edwards, Paul Henderson, Craig Mowat, Jeremy Sanderson, Jack Satsangi, Alison Simmons, David C. Wilson, Mark Tremelling, Ailsa Hart, Christopher G. Mathew, William G. Newman, Miles Parkes, Charlie W. Lees, Holm Uhlig, Chris Hawkey, Natalie J. Prescott, Tariq Ahmad, John C. Mansfield, Carl A. Anderson, Jeffrey C. Barrett
bioRxiv 058255; doi: https://doi.org/10.1101/058255
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