New Results
Analysis of shared heritability in common disorders of the brain
V Anttila, B Bulik-Sullivan, H Finucane, J Bras, L Duncan, V Escott-Price, G Falcone, P Gormley, R Malik, N Patsopoulos, S Ripke, R Walters, Z Wei, D Yu, PH Lee, IGAP consortium, IHGC consortium, ILAE Consortium on Complex Epilepsies, IMSGC consortium, IPDGC consortium, METASTROKE and ICH Studies of the ISGC, ADHD Working Group of the PGC, Anorexia Nervosa Working Group of the PGC, ASD Working Group of the PGC, Bipolar Disorders Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, OCD and TS Working Group of the PGC, Schizophrenia Working Group of the PGC, G Breen, C Bulik, M Daly, M Dichgans, S Faraone, R Guerreiro, P Holmans, K Kendler, B Koeleman, CA Mathews, JM Scharf, P Sklar, J Williams, N Wood, C Cotsapas, A Palotie, JW Smoller, P Sullivan, J Rosand, A Corvin, BM Neale, on behalf of the Brainstorm consortium
doi: https://doi.org/10.1101/048991
V Anttila
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
B Bulik-Sullivan
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
H Finucane
4Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
5Department of Epidemiology, Harvard T.H. ChanSchool of Public Health, Boston, Massachusetts, USA
J Bras
6Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
L Duncan
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
V Escott-Price
7Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, Wales, UK
G Falcone
8Center for Human Genetic Research, Departmentof Neurology, Massachusetts General Hospital, Boston, MA, USA
P Gormley
9Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
R Malik
10Institute for Stroke and Dementia Research,Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany
N Patsopoulos
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
11Department of Neurology, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA
S Ripke
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
12Charite Universitatsmedizin Berlin, Berlin,Germany
R Walters
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Z Wei
13Department of Computer Science, New Jersey Institute of Technology, New Jersey, USA
D Yu
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
9Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
PH Lee
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
9Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
G Breen
14Kings College London, Institute of Psychiatry, Psychology& Neuroscience, Social Genetics & Developmental Psychiatry Center, MRC, London, England
15NIHR, Biomed Research Center for Mental Health, South London & Maudsley NHS Trust & Institute Psychiatry, London, England
C Bulik
16Departments of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
17Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
M Daly
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
M Dichgans
10Institute for Stroke and Dementia Research,Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany
18Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
S Faraone
19Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA
R Guerreiro
20Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK
P Holmans
7Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, Wales, UK
K Kendler
21Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA
B Koeleman
22Division Biomedical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands
CA Mathews
23Department of Psychiatry and UF Genetics Institute, University of Florida: Gainesville, Florida, USA
JM Scharf
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
8Center for Human Genetic Research, Departmentof Neurology, Massachusetts General Hospital, Boston, MA, USA
9Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
24Division of Cognitive and Behavioral Neurology, Brigham and Women’s Hospital, Boston, MA, USA
25Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
P Sklar
26Icahn School of Medicine at Mount Sinai, New York, New York, USA
J Williams
7Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, Wales, UK
N Wood
20Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK
27Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK
28Institute of Genetics, University College London, London, UK
C Cotsapas
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
29Department of Neurology, Yale School of Medicine, New Haven, CT, USA
A Palotie
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
9Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
30Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland
31Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
JW Smoller
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
9Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA, USA
P Sullivan
16Departments of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
32Department of Genetics and Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
J Rosand
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
8Center for Human Genetic Research, Departmentof Neurology, Massachusetts General Hospital, Boston, MA, USA
25Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
A Corvin
33Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Ireland
BM Neale
1Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Article usage
Posted April 16, 2016.
Analysis of shared heritability in common disorders of the brain
V Anttila, B Bulik-Sullivan, H Finucane, J Bras, L Duncan, V Escott-Price, G Falcone, P Gormley, R Malik, N Patsopoulos, S Ripke, R Walters, Z Wei, D Yu, PH Lee, IGAP consortium, IHGC consortium, ILAE Consortium on Complex Epilepsies, IMSGC consortium, IPDGC consortium, METASTROKE and ICH Studies of the ISGC, ADHD Working Group of the PGC, Anorexia Nervosa Working Group of the PGC, ASD Working Group of the PGC, Bipolar Disorders Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, OCD and TS Working Group of the PGC, Schizophrenia Working Group of the PGC, G Breen, C Bulik, M Daly, M Dichgans, S Faraone, R Guerreiro, P Holmans, K Kendler, B Koeleman, CA Mathews, JM Scharf, P Sklar, J Williams, N Wood, C Cotsapas, A Palotie, JW Smoller, P Sullivan, J Rosand, A Corvin, BM Neale, on behalf of the Brainstorm consortium
bioRxiv 048991; doi: https://doi.org/10.1101/048991
Analysis of shared heritability in common disorders of the brain
V Anttila, B Bulik-Sullivan, H Finucane, J Bras, L Duncan, V Escott-Price, G Falcone, P Gormley, R Malik, N Patsopoulos, S Ripke, R Walters, Z Wei, D Yu, PH Lee, IGAP consortium, IHGC consortium, ILAE Consortium on Complex Epilepsies, IMSGC consortium, IPDGC consortium, METASTROKE and ICH Studies of the ISGC, ADHD Working Group of the PGC, Anorexia Nervosa Working Group of the PGC, ASD Working Group of the PGC, Bipolar Disorders Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, OCD and TS Working Group of the PGC, Schizophrenia Working Group of the PGC, G Breen, C Bulik, M Daly, M Dichgans, S Faraone, R Guerreiro, P Holmans, K Kendler, B Koeleman, CA Mathews, JM Scharf, P Sklar, J Williams, N Wood, C Cotsapas, A Palotie, JW Smoller, P Sullivan, J Rosand, A Corvin, BM Neale, on behalf of the Brainstorm consortium
bioRxiv 048991; doi: https://doi.org/10.1101/048991
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