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Atomic structure of Hsp90:Cdc37:Cdk4 reveals Hsp90 regulates kinase via dramatic unfolding
Kliment A. Verba, Ray Yu-Ruei Wang, Akihiko Arakawa, Yanxin Liu, Mikako Shirouzu, Shigeyuki Yokoyama, David A. Agard
doi: https://doi.org/10.1101/040907
Kliment A. Verba
1Howard Hughes Medical Institute and the Department of Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
Ray Yu-Ruei Wang
1Howard Hughes Medical Institute and the Department of Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
Akihiko Arakawa
2RIKEN Systems and Structural Biology Center, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan
Yanxin Liu
1Howard Hughes Medical Institute and the Department of Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
Mikako Shirouzu
2RIKEN Systems and Structural Biology Center, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan
Shigeyuki Yokoyama
2RIKEN Systems and Structural Biology Center, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan
David A. Agard
1Howard Hughes Medical Institute and the Department of Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
Article usage
Posted February 25, 2016.
Atomic structure of Hsp90:Cdc37:Cdk4 reveals Hsp90 regulates kinase via dramatic unfolding
Kliment A. Verba, Ray Yu-Ruei Wang, Akihiko Arakawa, Yanxin Liu, Mikako Shirouzu, Shigeyuki Yokoyama, David A. Agard
bioRxiv 040907; doi: https://doi.org/10.1101/040907
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