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Human Longevity is Influenced by Many Genetic Variants: Evidence from 75,000 UK Biobank Participants
Luke C. Pilling, Janice L. Atkins, Kirsty Bowman, Samuel E. Jones, Jessica Tyrrell, Robin N. Beaumont, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Andrew R. Wood, Rachel M. Freathy, Anna Murray, Michael N. Weedon, Luting Xue, Kathryn Lunetta, Joanne M. Murabito, Lorna W. Harries, Jean-Marie Robine, Carol Brayne, George A. Kuchel, Luigi Ferrucci, Timothy M. Frayling, David Melzer
doi: https://doi.org/10.1101/038430
Luke C. Pilling
1Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Janice L. Atkins
1Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Kirsty Bowman
1Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Samuel E. Jones
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Jessica Tyrrell
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Robin N. Beaumont
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Katherine S. Ruth
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Marcus A. Tuke
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Hanieh Yaghootkar
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Andrew R. Wood
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Rachel M. Freathy
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Anna Murray
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Michael N. Weedon
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
Luting Xue
3School of Public Health, Department of Biostatistics, Boston University, Boston, MA, USA
Kathryn Lunetta
3School of Public Health, Department of Biostatistics, Boston University, Boston, MA, USA
4The Framingham Heart Study, 73 Mt. Wayte Ave. Suite #2, Framingham, MA 01702, USA
Joanne M. Murabito
4The Framingham Heart Study, 73 Mt. Wayte Ave. Suite #2, Framingham, MA 01702, USA
5Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA
Lorna W. Harries
6Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, UK
Jean-Marie Robine
7Institut National de la Sante et de la Recherché Medicale, Demographie et Santé du Departement de Biostatistiques, Montpellier, France
Carol Brayne
8Cambridge Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, UK
George A. Kuchel
9Center on Aging, University of Connecticut, 263 Farmington Avenue, Farmington, CT 060305215, USA.
Luigi Ferrucci
10National Institute on Aging, Baltimore, MD, United States.
Timothy M. Frayling
2Genetics of Complex Traits, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
David Melzer
1Epidemiology and Public Health Group, University of Exeter Medical School, RILD Level 3, Royal Devon & Exeter Hospital, Barrack Road, Exeter, EX2 5DW, UK.
3School of Public Health, Department of Biostatistics, Boston University, Boston, MA, USA
Article usage
Posted February 01, 2016.
Human Longevity is Influenced by Many Genetic Variants: Evidence from 75,000 UK Biobank Participants
Luke C. Pilling, Janice L. Atkins, Kirsty Bowman, Samuel E. Jones, Jessica Tyrrell, Robin N. Beaumont, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Andrew R. Wood, Rachel M. Freathy, Anna Murray, Michael N. Weedon, Luting Xue, Kathryn Lunetta, Joanne M. Murabito, Lorna W. Harries, Jean-Marie Robine, Carol Brayne, George A. Kuchel, Luigi Ferrucci, Timothy M. Frayling, David Melzer
bioRxiv 038430; doi: https://doi.org/10.1101/038430
Human Longevity is Influenced by Many Genetic Variants: Evidence from 75,000 UK Biobank Participants
Luke C. Pilling, Janice L. Atkins, Kirsty Bowman, Samuel E. Jones, Jessica Tyrrell, Robin N. Beaumont, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Andrew R. Wood, Rachel M. Freathy, Anna Murray, Michael N. Weedon, Luting Xue, Kathryn Lunetta, Joanne M. Murabito, Lorna W. Harries, Jean-Marie Robine, Carol Brayne, George A. Kuchel, Luigi Ferrucci, Timothy M. Frayling, David Melzer
bioRxiv 038430; doi: https://doi.org/10.1101/038430
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