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Hypothesis-free identification of modulators of genetic risk factors
Daria V. Zhernakova, View ORCID ProfilePatrick Deelen, View ORCID ProfileMartijn Vermaat, View ORCID ProfileMaarten van Iterson, View ORCID ProfileMichiel van Galen, View ORCID ProfileWibowo Arindrarto, View ORCID ProfilePeter van ‘t Hof, View ORCID ProfileHailiang Mei, View ORCID ProfileFreerk van Dijk, View ORCID ProfileHarm-Jan Westra, View ORCID ProfileMarc Jan Bonder, View ORCID ProfileJeroen van Rooij, View ORCID ProfileMarijn Verkerk, View ORCID ProfileP. Mila Jhamai, View ORCID ProfileMatthijs Moed, View ORCID ProfileSzymon M. Kielbasa, View ORCID ProfileJan Bot, View ORCID ProfileIrene Nooren, View ORCID ProfileRené Pool, View ORCID ProfileJenny van Dongen, View ORCID ProfileJouke J. Hottenga, View ORCID ProfileCoen D.A. Stehouwer, View ORCID ProfileCarla J.H. van der Kallen, View ORCID ProfileCasper G. Schalkwijk, View ORCID ProfileAlexandra Zhernakova, View ORCID ProfileYang Li, View ORCID ProfileEttje F. Tigchelaar, View ORCID ProfileMarian Beekman, View ORCID ProfileJoris Deelen, View ORCID ProfileDiana van Heemst, View ORCID ProfileLeonard H. van den Berg, View ORCID ProfileAlbert Hofman, View ORCID ProfileAndré G. Uitterlinden, View ORCID ProfileMarleen M.J. van Greevenbroek, View ORCID ProfileJan H. Veldink, View ORCID ProfileDorret I. Boomsma, View ORCID ProfileCornelia M. van Duijn, View ORCID ProfileCisca Wijmenga, View ORCID ProfileP. Eline Slagboom, View ORCID ProfileMorris A. Swertz, View ORCID ProfileAaron Isaacs, View ORCID ProfileJoyce B.J. van Meurs, View ORCID ProfileRick Jansen, View ORCID ProfileBastiaan T. Heijmans, View ORCID ProfilePeter A.C. ‘t Hoen, View ORCID ProfileLude Franke
doi: https://doi.org/10.1101/033217
Daria V. Zhernakova
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
Patrick Deelen
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
2University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands
Martijn Vermaat
3Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands
Maarten van Iterson
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Michiel van Galen
3Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands
Wibowo Arindrarto
5Sequence Analysis Support Core, Leiden University Medical Center, Leiden, the Netherlands
Peter van ‘t Hof
5Sequence Analysis Support Core, Leiden University Medical Center, Leiden, the Netherlands
Hailiang Mei
5Sequence Analysis Support Core, Leiden University Medical Center, Leiden, the Netherlands
Freerk van Dijk
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
2University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands
Harm-Jan Westra
6Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, USA
7Partners Center for Personalized Genetic Medicine, Boston, USA
8Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, USA
Marc Jan Bonder
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
Jeroen van Rooij
9Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands
Marijn Verkerk
9Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands
P. Mila Jhamai
9Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands
Matthijs Moed
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Szymon M. Kielbasa
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Jan Bot
10SURFsara, Amsterdam, the Netherlands
Irene Nooren
10SURFsara, Amsterdam, the Netherlands
René Pool
11Department of Biological Psychology, VU Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands
Jenny van Dongen
11Department of Biological Psychology, VU Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands
Jouke J. Hottenga
11Department of Biological Psychology, VU Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands
Coen D.A. Stehouwer
12Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands
Carla J.H. van der Kallen
12Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands
Casper G. Schalkwijk
12Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands
Alexandra Zhernakova
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
Yang Li
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
Ettje F. Tigchelaar
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
Marian Beekman
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Joris Deelen
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Diana van Heemst
13Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands
Leonard H. van den Berg
14Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
Albert Hofman
15Department of Epidemiology, ErasmusMC, Rotterdam, the Netherlands
André G. Uitterlinden
9Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands
Marleen M.J. van Greevenbroek
12Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, the Netherlands
Jan H. Veldink
16Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
Dorret I. Boomsma
11Department of Biological Psychology, VU Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands
Cornelia M. van Duijn
17Genetic Epidemiology Unit, Department of Epidemiology, ErasmusMC, Rotterdam, the Netherlands
Cisca Wijmenga
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
P. Eline Slagboom
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Morris A. Swertz
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
2University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, the Netherlands
Aaron Isaacs
17Genetic Epidemiology Unit, Department of Epidemiology, ErasmusMC, Rotterdam, the Netherlands
18CARIM School for Cardiovascular Diseases and Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, the Netherlands
Joyce B.J. van Meurs
9Department of Internal Medicine, ErasmusMC, Rotterdam, The Netherlands
Rick Jansen
19Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands
Bastiaan T. Heijmans
4Molecular Epidemiology Section, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands
Peter A.C. ‘t Hoen
3Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands
Lude Franke
1University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands
Article usage
Posted November 30, 2015.
Hypothesis-free identification of modulators of genetic risk factors
Daria V. Zhernakova, Patrick Deelen, Martijn Vermaat, Maarten van Iterson, Michiel van Galen, Wibowo Arindrarto, Peter van ‘t Hof, Hailiang Mei, Freerk van Dijk, Harm-Jan Westra, Marc Jan Bonder, Jeroen van Rooij, Marijn Verkerk, P. Mila Jhamai, Matthijs Moed, Szymon M. Kielbasa, Jan Bot, Irene Nooren, René Pool, Jenny van Dongen, Jouke J. Hottenga, Coen D.A. Stehouwer, Carla J.H. van der Kallen, Casper G. Schalkwijk, Alexandra Zhernakova, Yang Li, Ettje F. Tigchelaar, Marian Beekman, Joris Deelen, Diana van Heemst, Leonard H. van den Berg, Albert Hofman, André G. Uitterlinden, Marleen M.J. van Greevenbroek, Jan H. Veldink, Dorret I. Boomsma, Cornelia M. van Duijn, Cisca Wijmenga, P. Eline Slagboom, Morris A. Swertz, Aaron Isaacs, Joyce B.J. van Meurs, Rick Jansen, Bastiaan T. Heijmans, Peter A.C. ‘t Hoen, Lude Franke
bioRxiv 033217; doi: https://doi.org/10.1101/033217
Hypothesis-free identification of modulators of genetic risk factors
Daria V. Zhernakova, Patrick Deelen, Martijn Vermaat, Maarten van Iterson, Michiel van Galen, Wibowo Arindrarto, Peter van ‘t Hof, Hailiang Mei, Freerk van Dijk, Harm-Jan Westra, Marc Jan Bonder, Jeroen van Rooij, Marijn Verkerk, P. Mila Jhamai, Matthijs Moed, Szymon M. Kielbasa, Jan Bot, Irene Nooren, René Pool, Jenny van Dongen, Jouke J. Hottenga, Coen D.A. Stehouwer, Carla J.H. van der Kallen, Casper G. Schalkwijk, Alexandra Zhernakova, Yang Li, Ettje F. Tigchelaar, Marian Beekman, Joris Deelen, Diana van Heemst, Leonard H. van den Berg, Albert Hofman, André G. Uitterlinden, Marleen M.J. van Greevenbroek, Jan H. Veldink, Dorret I. Boomsma, Cornelia M. van Duijn, Cisca Wijmenga, P. Eline Slagboom, Morris A. Swertz, Aaron Isaacs, Joyce B.J. van Meurs, Rick Jansen, Bastiaan T. Heijmans, Peter A.C. ‘t Hoen, Lude Franke
bioRxiv 033217; doi: https://doi.org/10.1101/033217
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